Can I eat grapefruit while taking Zoloft?

Can I eat grapefruit while taking Zoloft?

Can I eat grapefruit while taking Zoloft?

Anti-anxiety medications such as sertraline (Zoloft), buspirone (Buspar), and diazepam (Valium) can cause drowsiness or dizziness when taken with grapefruit juice.19 Feb 2019

Does grapefruit juice affect methadone?

Conclusions: Grapefruit juice inhibits the metabolism of methadone, raising its serum levels. To our knowledge, this is the first reported case in which the interaction between grapefruit juice and methadone was significant enough to cause an opioid toxidrome.

How does Zoloft interact with grapefruit?

  • There is a known interaction between grapefruit (and grapefruit juice) and Zoloft (sertraline). Grapefruit has been shown to affect Zoloft (sertraline) concentrations via inhibition of the CYP3A enzyme. Inhibition of this enzyme can potentially elevate Zoloft (sertraline) levels in the body, increasing the risk of adverse reactions.

What medications are contraindicated with grapefruit?

  • Grapefruit might interact with some of these medications including lovastatin (Mevacor), simvastatin (Zocor), and atorvastatin (Lipitor), But grapefruit juice does not interact with some other medications used for lowering cholesterol including pravastatin (Pravachol), fluvastatin (Lescol), and rosuvastatin (Crestor).

When should you not eat grapefruit?

  • Grapefruit contains a huge amount of acid. If you eat it when you’re hungry, it will hurt your stomach, especially for people who are applying a type of weight loss with grapefruit. Therefore, you should only eat grapefruit when you have eaten something.

Why is grapefruit bad with medication?

  • The grapefruit ( Citrus x paradisi) and its juice contain chemicals that interfere with CYP3A4 and keep it from doing its job properly. Depending on the medication, it can either cause your body to take in and retain too much of the drug, leading to a potential overdose, or not enough, rendering your medication useless.

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