How grapefruit affects medication?

How grapefruit affects medication?

How grapefruit affects medication?

Many drugs are broken down (metabolized) with the help of a vital enzyme called CYP3A4 in the small intestine. Grapefruit juice can block the action of intestinal CYP3A4, so instead of being metabolized, more of the drug enters the blood and stays in the body longer. The result: too much drug in your body. BE

What medications are contraindicated with grapefruit?

  • Grapefruit might interact with some of these medications including lovastatin (Mevacor), simvastatin (Zocor), and atorvastatin (Lipitor), But grapefruit juice does not interact with some other medications used for lowering cholesterol including pravastatin (Pravachol), fluvastatin (Lescol), and rosuvastatin (Crestor).

Why no grapefruit with buspirone?

  • Do not drink large amounts of grapefruit juice while you are on buspirone. This is because grapefruit juice can interfere with the enzymes that break down buspirone in your digestive system. This may result in your body absorbing more of the medicine than intended. It will increase the risk of side-effects.

When should you not eat grapefruit?

  • Grapefruit contains a huge amount of acid. If you eat it when you’re hungry, it will hurt your stomach, especially for people who are applying a type of weight loss with grapefruit. Therefore, you should only eat grapefruit when you have eaten something.

When you should not eat grapefruit?

  • If you're on blood pressure medication, you should avoid eating grapefruit. The reason why is that grapefruit is very acidic and breaks down certain medications much faster. For some people, this causes them to absorb too much of the medicine and for others, not enough.

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